Cholesterol Lowering Drugs - 'Statins' - Learn How They Work and The Effects They Produce

Cholesterol lowering drugs - commonly called statins - are being prescribed frequently, but the side effects they produce in the body can leave you feeling achy, fatigued, and depressed. What should you do? If you feel caught between a rock and a hard place, answering the following two questions should help you decide: 'How do statins work?' and 'Are they effective?'

Statins work by inhibiting an enzyme called HMG-CoA reductase. This enzyme works in the liver and is essential for producing cholesterol and another co-enzyme called COQ10. When HMG-CoA is inhibited, the liver is inhibited, and cannot perform its functions properly - cholesterol and COQ10 levels in the body are both depleted.

To understand what happens when cholesterol levels are reduced, we need to understand the role cholesterol plays in our bodies. Cholesterol is a substance that is found in every cell membrane, making our cell walls waterproof. Without sufficient cholesterol, our cell walls become leaky. Studies have shown that low cholesterol rates yield increased rates of cancer. That should not be surprising, since cancer begins at the cell level. Cholesterol is also a repair substance. It is found in all scar tissue, including the scar tissue that is in your arteries - plaque. (This fact should help us to realize that cholesterol is a symptom of heart disease, not a cause). Cholesterol is also needed by our brains for proper brain function. What am I getting at? Cholesterol is a friend, not a foe. Creating low levels of cholesterol, inhibiting its normal, necessary functions can be very dangerous to your health.

Statins also interfere with the making of the enzyme COQ10. COQ10, like cholesterol, is found in our cells, and is vital for the creation of ATP in the mitochondria. The creation of ATP (energy) is crucial for cell reproduction, cell repair, for the effective messaging and interaction between our cells -ie- our immune system, and for supporting muscle function. When COQ10 levels are depleted, our muscles can not function properly. Since the heart is a muscle, it is directly affected when COQ10 is limited. Though statins are taken to reduce cholesterol levels and thereby increase heart function, indirectly they may decrease heart function by altering COQ10 levels. It is interesting to note that deaths due to heart failure doubled from 1989-1997. Statins were introduced to the American public in 1987.

Do statins work? It depends on what you want them to do. Yes, they lower cholesterol levels.

Do they prevent heart disease? It is evident that heart disease is not on the decline. This is affirmed by a test done in 1992, in which Dr Ravnskov analyzed 26 controlled cholesterol lowering trials and found an equal number of cardiovascular deaths in both the treatment and the control groups.1

Are statins effective? They lower cholesterol and COQ10 very effectively, but do not seem to be lowering rates of heart disease. You need to have the right cause to produce the right effect. Evidence seems to indicate that factors other than high cholesterol are causing heart disease. If high cholesterol caused heart disease, then statins would be putting a large dent into the number of heart disease victims --but they're not. Instead they are causing problems all their own. I'll be saving that information for future articles...

If you decide to take statins, you should supplement with COQ10, or you will be at risk for very serious side effects, particularly wasting of your muscles. If you choose not to take statins, there are some very effective natural remedies that can help bring your cholesterol/ triglyceride levels into a normal range, by getting to the source of the problem. They would be a much wiser investment, in my opinion.

1. Ravnskov U.BMJ.1992;305:15-19

The information in this article is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment.

You are encouraged to confirm any information obtained from or through this article with other sources, and review all information regarding any medical condition or treatment with your physician.

I research information concerning current health trends, inform people of the myths that are being circulated, and provide natural remedies that will dramatically increase the potential for living disease free.

I am a wife, the mother of 5 and the grandmother of six girls.

http://www.haveahealthyheartnow.com/

Original article

Prescription Drugs Versus Natural Diets To Lower Cholesterol Levels

These myths can be listed thus:-
Cholesterol is not as bad as many have made it out to be. It is needed by the body to produce hormones such as testesterone and estrogen.
Bad cholesterol in the system does not necessarily lead to heart disease. Other mental and physical factors such as stress, exercise or body weight can be the cause of elevated bad cholesterol in the blood.
High cholesterol is not responsible for arteriosclerosis, the condition when plaque (comprising hardened cholesterol) begins to form and attach itself to the walls of blood vessels.
No particular diet can reduce bad cholesterol as the body produces much more bad cholesterol than any food can deal with.
Heavy consumption of animal fat as a result of meat consumption will not cause arteriosclerosis, so that consuming animal fat will not bring about heart disease.
Cholesterol management drugs do not lead to the increased mortality of persons consuming them and
Cholesterol management drugs do have certain side effects which can be effectively managed with other drugs and one has to find the drugs that are best suited by trial and error.

The cholesterol management drug market is a US$16 Billion market. It is therefore not surprising that some money will be spent promoting these drugs in the best light. There is also a huge market for those drugs that will treat with the side effects. The main side effects that have been documented include cancer risk, general weakness, immune system suppression, and muscle and kidney damage.

It is worth taking a little time to list the range of side effects that statin drugs have on the human body as reported. The first major side effect is the effect that the drug has on the liver. After a while the liver does not function as it should. This does happen in a small fraction of users and the physician has to take specific blood tests on a regular basis to monitor this problem. The next major side effect is called myopathy which is a condition where the muscle tissue is affected. Great pain is experienced and if the drugs are continued there is a condition called rhabdomyolysis which develops that can result in death.

Taking statin drugs with other drugs can also be very dangerous. A combination of statins with antibiotics or anti-fungals have been known to present many problems for the body. Taking grapefruit juice together statins is a definite no-no. This combination actually increases cholesterol levels in the bloodstream.

Statin drugs have also been reported to affect one's ability to concentrate, to remember and to think. They have also been known to induce depression. Statins have been reported to cause recurring headaches, joint pain, abdominal pain, numbness and tingling in one's hands and feet.

Other side effects reported include sleep problems, dizziness, a sense of detachment, swelling, shortness of breath, changes in vision, weight change, hunger, breast enlargement, blood sugar changes, dry skin, rashes, blood pressure changes, nausea, upset stomach, bleeding and ring in the ears.

The other aspect of these drugs are that they are quite expensive and not affordable to the common man. Companies claim that they have to reclaim their research and development outlay and that is why prices are so high.

Natural Super-Foods With No Side Effects.

There are a number of natural super-foods that if consumed regularly will lead to lower cholesterol level with absolutely no side effects. These foods in alphabetical order include almonds, apples, artichokes, avocadoes, beans, carrots, chocolates, oats, olive oil, onions, popcorn and fatty fish. There are a number of natural supplements that have been found to be very effective so much so that the drug manufacturers are using them in their next generation of cholesterol management drugs.

As always you must check with your physician before changing your diet program.

Nigel Gittens is a writer and researcher on Nutrition. For more great information on lower cholesterol, visit http://www.lowercholesterolstrategies.com/

Original article